Prof. Dr. Dieter Saur

Medicine II, Klinikum rechts der Isar, Technical University Munich, Ismaningerstra?e 22, 81675 Munich, Germany; German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany

Gastrointestinal cancer �C Molecular mechanisms of tumor development, maintenance, metastasis and treatment resistance
Generation and analysis of genetically engineered inducible and switchable models for gastrointestinal cancer subtypes (pancreatic cancer, colon cancer, bile duct cancer, liver cancer)
Tissue specific retroviral gene transfer
Discovery of genes and signaling pathways crucial for tumor maintenance, tissue-specific metastasis and treatment resistance
Tumor-stroma and tumor-immune system interactions
Tumor progression and metastasis of GI cancer
Discovery and validation of new targets for treatment of GI cancer

Molecular imaging of gastrointestinal cancer
Optical (bioluminescence- and fluorescence) imaging in animal models of GI cancer
Molecular endoscopic imaging in humans

Neurogastroenterology
Molecular and cellular mechanisms of nitric-oxide signaling in the gut
Genetic analysis of interstitial cells of Cajal (ICC) using the Cre/loxP system
Genetic basis of motility disorders